What repeat expansion disorders can teach us about the Central Dogma
Pathogenic repeat sequences underlie several human disorders, including amyotrophic lateral sclerosis, Huntington's disease, and myotonic dystrophy. Here, we speak to several researchers about how repeat sequences have been implicated in affecting all aspects of the Central Dogma of molecular b...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2023
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| _version_ | 1826312093772546048 |
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| author | Wang, ET Freudenreich, CH Gromak, N Jain, A Todd, PK Nagai, Y |
| author_facet | Wang, ET Freudenreich, CH Gromak, N Jain, A Todd, PK Nagai, Y |
| author_sort | Wang, ET |
| collection | OXFORD |
| description | Pathogenic repeat sequences underlie several human disorders, including amyotrophic lateral sclerosis, Huntington's disease, and myotonic dystrophy. Here, we speak to several researchers about how repeat sequences have been implicated in affecting all aspects of the Central Dogma of molecular biology through their effects on DNA, RNA, and protein. |
| first_indexed | 2024-03-07T08:22:26Z |
| format | Journal article |
| id | oxford-uuid:f38ac98c-e354-4169-923b-80a8aba1f310 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:22:26Z |
| publishDate | 2023 |
| publisher | Cell Press |
| record_format | dspace |
| spelling | oxford-uuid:f38ac98c-e354-4169-923b-80a8aba1f3102024-02-02T07:27:52ZWhat repeat expansion disorders can teach us about the Central DogmaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f38ac98c-e354-4169-923b-80a8aba1f310EnglishSymplectic ElementsCell Press2023Wang, ETFreudenreich, CHGromak, NJain, ATodd, PKNagai, YPathogenic repeat sequences underlie several human disorders, including amyotrophic lateral sclerosis, Huntington's disease, and myotonic dystrophy. Here, we speak to several researchers about how repeat sequences have been implicated in affecting all aspects of the Central Dogma of molecular biology through their effects on DNA, RNA, and protein. |
| spellingShingle | Wang, ET Freudenreich, CH Gromak, N Jain, A Todd, PK Nagai, Y What repeat expansion disorders can teach us about the Central Dogma |
| title | What repeat expansion disorders can teach us about the Central Dogma |
| title_full | What repeat expansion disorders can teach us about the Central Dogma |
| title_fullStr | What repeat expansion disorders can teach us about the Central Dogma |
| title_full_unstemmed | What repeat expansion disorders can teach us about the Central Dogma |
| title_short | What repeat expansion disorders can teach us about the Central Dogma |
| title_sort | what repeat expansion disorders can teach us about the central dogma |
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