Genetic insights into the hypoxia-inducible factor (HIF) pathway.
The HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified...
| Main Authors: | , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
2007
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| _version_ | 1826304837038374912 |
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| author | Kiriakidis, S Esteban, M Maxwell, P |
| author_facet | Kiriakidis, S Esteban, M Maxwell, P |
| author_sort | Kiriakidis, S |
| collection | OXFORD |
| description | The HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified in human populations, which are likely to be important in disease susceptibility. © 2006 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-07T06:23:48Z |
| format | Journal article |
| id | oxford-uuid:f39474f2-ea02-4c07-a08e-01138f42b35d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:23:48Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:f39474f2-ea02-4c07-a08e-01138f42b35d2022-03-27T12:13:09ZGenetic insights into the hypoxia-inducible factor (HIF) pathway.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f39474f2-ea02-4c07-a08e-01138f42b35dEnglishSymplectic Elements at Oxford2007Kiriakidis, SEsteban, MMaxwell, PThe HIF system probably operates in all cells, in all metazoan organisms. The effects of genetic alterations in the main components of the pathway offer a very powerful way to delineate its function in normal biology and disease. With time it is likely that more subtle variations will be identified in human populations, which are likely to be important in disease susceptibility. © 2006 Elsevier Ltd. All rights reserved. |
| spellingShingle | Kiriakidis, S Esteban, M Maxwell, P Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title | Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title_full | Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title_fullStr | Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title_full_unstemmed | Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title_short | Genetic insights into the hypoxia-inducible factor (HIF) pathway. |
| title_sort | genetic insights into the hypoxia inducible factor hif pathway |
| work_keys_str_mv | AT kiriakidiss geneticinsightsintothehypoxiainduciblefactorhifpathway AT estebanm geneticinsightsintothehypoxiainduciblefactorhifpathway AT maxwellp geneticinsightsintothehypoxiainduciblefactorhifpathway |