Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region.

Stimulation of the NF-kappaB pathway often causes p65-p50 and p50-p50 dimers to be simultaneously present in the cell nucleus. A natural polymorphism at nucleotide -863 in the human TNF promoter (encoding tumor necrosis factor [TNF]) region provides an opportunity to dissect the functional interacti...

全面介绍

书目详细资料
Main Authors: Udalova, I, Richardson, A, Denys, A, Smith, C, Ackerman, H, Foxwell, B, Kwiatkowski, D
格式: Journal article
语言:English
出版: 2000