Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever

We have previously demonstrated that Mucosal-Associated Invariant T (MAIT) cells secrete multiple cytokines after exposure to Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever in humans. However, whether cytokine secreting MAIT cells can enhance or attenuate the clin...

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Autors principals: Salerno-Gonçalves, R, Fresnay, S, Magder, L, Darton, TC, Waddington, CS, Blohmke, CJ, Angus, B, Levine, MM, Pollard, AJ, Sztein, MB
Format: Journal article
Idioma:English
Publicat: Elsevier 2022