Repurposing of synaptonemal complex proteins for kinetochores in kinetoplastida

Chromosome segregation in eukaryotes is driven by the kinetochore, a macromolecular complex that connects centromeric DNA to microtubules of the spindle apparatus. Kinetochores in well-studied model eukaryotes consist of a core set of proteins that are broadly conserved among distant eukaryotic phyl...

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Autori principali: Tromer, E, Wemyss, T, Ludzia, P, Waller, R, Akiyoshi, B
Natura: Journal article
Lingua:English
Pubblicazione: Royal Society, The 2021