"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate

BACKGROUND: While intracellular buffers are widely used to study calcium signaling, no such tool exists for the other major second messenger, cyclic AMP (cAMP). METHODS/PRINCIPAL FINDINGS: Here we describe a genetically encoded buffer for cAMP based on the high-affinity cAMP-binding carboxy-terminu...

Full description

Bibliographic Details
Main Authors: Lefkimmiatis, K, Moyer, M, Curci, S, Hofer, A
Format: Journal article
Language:English
Published: Public Library of Science 2009