Fine-tuned photochromic sulfonylureas for optical control of beta cell Ca2+ fluxes

We previously developed, synthesized and tested light-activated sulfonylureas for optical control of KATP channels and pancreatic beta cell activity in vitro and in vivo. Such technology relies on installation of azobenzene photoswitches onto the sulfonylurea backbone, affording light-dependent isom...

Full description

Bibliographic Details
Main Authors: Rückert, A-K, Ast, J, Hasib, A, Nasteska, D, Viloria, K, Broichhagen, J, Hodson, DJ
Format: Journal article
Language:English
Published: Wiley 2023