Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells
The intracellular environment hosts a large number of cancer- and other disease-relevant human proteins. Targeting these with internalized antibodies would allow therapeutic modulation of hitherto undruggable pathways, such as those mediated by protein–protein interactions. However, one of the major...
Autors principals: | Tietz, O, Cortezon Tamarit, F, Chalk, R, Able, S, Vallis, K |
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Format: | Journal article |
Idioma: | English |
Publicat: |
Springer Nature
2022
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