Visualization of activated platelets by targeted magnetic resonance imaging utilizing conformation-specific antibodies against glycoprotein IIb/IIIa.

Ruptured atherosclerotic plaques, lined with activated platelets, constitute an attractive target for magnetic resonance imaging (MRI). This study evaluated whether microparticles of iron oxide (MPIO) targeting ligand-induced binding sites (LIBS) on the activated conformation of glycoprotein IIb/III...

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Bibliografski detalji
Glavni autori: von zur Muhlen, C, Peter, K, Ali, ZA, Schneider, JE, McAteer, MA, Neubauer, S, Channon, KM, Bode, C, Choudhury, RP
Format: Journal article
Jezik:English
Izdano: Karger Publishers 2009