Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven approaches to find optimal patient-specific treatments. Here we report As...

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Bibliographic Details
Main Authors: Menden, MP, Wang, D, Mason, MJ, Szalai, B, Bulusu, KC, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang, IS, Ghazoui, Z, Ahsen, ME, Vogel, R, Neto, EC, Norman, T, Tang, EKY, Garnett, MJ, Veroli, GYD, Fawell, S, Stolovitzky, G, Guinney, J, Dry, JR, Saez-Rodriguez, J
Other Authors: Hu, Z
Format: Journal article
Language:English
Published: Springer Nature 2019