Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex.

Presentation of cytoplasmic antigens to class I-restricted cytotoxic T cells implied the existence of a specialized peptide transporter. For most class I heavy chains, association with peptides of the appropriate length is required for stable assembly with beta 2-microglobulin. Mutant cells RMA-S an...

Full description

Bibliographic Details
Main Authors: Kelly, A, Powis, S, Kerr, L, Mockridge, I, Elliott, T, Bastin, J, Uchanska-Ziegler, B, Ziegler, A, Trowsdale, J, Townsend, A
Format: Journal article
Language:English
Published: 1992