The immunological synapse: integrins take the stage.
Adhesive interactions play important roles in coordinating T-cell migration and activation, specifically in the formation of the immunological synapse (IS), a specialized cell-cell junction. Recent demonstrations show several molecules implicated in T-cell signaling, including Vav, ADAP, and Rap-1,...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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