Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.

Previously published literature reports various impacts of food on the oral bioavailability of piperaquine. The aim of this study was to use a population modeling approach to investigate the impact of concomitant intake of a small amount of food on piperaquine pharmacokinetics. This was an open, ran...

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Bibliographic Details
Main Authors: Tarning, J, Lindegardh, N, Lwin, K, Annerberg, A, Kiricharoen, L, Ashley, E, White, N, Nosten, F, Day, N
Format: Journal article
Language:English
Published: American Society for Microbiology 2014