Streamlining homogeneous glycoprotein production for biophysical and structural applications by targeted cell line development

Studying the biophysical characteristics of glycosylated proteins and solving their three-dimensional structures requires homogeneous recombinant protein of high quality.We introduce here a new approach to produce glycoproteins in homogenous form with the well-established, glycosylation mutant CHO L...

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Bibliographic Details
Main Authors: Wilke, S, Groebe, L, Maffenbeier, V, Jäger, V, Gossen, M, Josewski, J, Duda, A, Polle, L, Owens, R, Wirth, D, Heinz, D, van den Heuvel, J, Büssow, K
Format: Journal article
Language:English
Published: 2011