Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites.
We explored the potential of pooled sequencing to swiftly and economically identify selective sweeps due to emerging artemisinin (ART) resistance in a South-East Asian malaria parasite population. ART resistance is defined by slow parasite clearance from the blood of ART-treated patients and mutatio...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2014
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