Potassium channels: watching a voltage-sensor tilt and twist.

The fourth transmembrane helix (S4) is the primary voltage-sensor of voltage-gated ion channels. Recent studies have used fluorescence resonance energy transfer as a spectroscopic ruler to determine the nature and magnitude of the voltage-induced movement of S4 that leads to channel opening.

Bibliographic Details
Main Author: Sansom, MS
Format: Journal article
Language:English
Published: 2000