Potassium channels: watching a voltage-sensor tilt and twist.
The fourth transmembrane helix (S4) is the primary voltage-sensor of voltage-gated ion channels. Recent studies have used fluorescence resonance energy transfer as a spectroscopic ruler to determine the nature and magnitude of the voltage-induced movement of S4 that leads to channel opening.
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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