Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
Elucidating the rules for receptor triggering in cell-cell and cell-matrix contacts requires precise control of ligand positioning in three dimensions. Here, we use the T cell receptor (TCR) as a model and subject T cells to different geometric arrangements of ligands, using a nanofabricated single-...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2018
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