Response of serum macrophage migration inhibitory factor levels to stimulation or suppression of the hypothalamo-pituitary-adrenal axis in normal subjects and patients with Cushing's disease.

Macrophage migration inhibitory factor (MIF) is a proinflammatory pituitary and immune cell cytokine and a critical mediator of septic shock. It has been reported that MIF is secreted in parallel with ACTH from the pituitary in response to stress or inflammatory stimuli. MIF release from immune cell...

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Bibliographic Details
Main Authors: Isidori, A, Kaltsas, G, Korbonits, M, Pyle, M, Gueorguiev, M, Meinhardt, A, Metz, C, Petrovsky, N, Popovic, V, Bucala, R, Grossman, AB
Format: Journal article
Language:English
Published: 2002