Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.

BACKGROUND: The cross-talk between pathogenic T lymphocytes and regulatory T cells (Tregs) plays a major role in the progression of autoimmune diseases. Our objective is to identify molecules and/or pathways involved in this interaction and representing potential targets for innovative therapies. Gl...

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Bibliographic Details
Main Authors: You, S, Poulton, L, Cobbold, S, Liu, C, Rosenzweig, M, Ringler, D, Lee, W, Segovia, B, Bach, J, Waldmann, H, Chatenoud, L
Format: Journal article
Language:English
Published: 2009