Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.
BACKGROUND: The cross-talk between pathogenic T lymphocytes and regulatory T cells (Tregs) plays a major role in the progression of autoimmune diseases. Our objective is to identify molecules and/or pathways involved in this interaction and representing potential targets for innovative therapies. Gl...
Main Authors: | You, S, Poulton, L, Cobbold, S, Liu, C, Rosenzweig, M, Ringler, D, Lee, W, Segovia, B, Bach, J, Waldmann, H, Chatenoud, L |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2009
|
Similar Items
-
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target.
by: Sylvaine You, et al.
Published: (2009-11-01) -
In vivo kinetics of GITR, GITR-L expression and their functional significance in regulating viral immunopathology
by: Suvas, S, et al.
Published: (2005) -
The Role of GITR/GITRL Interaction in Autoimmune Diseases
by: Jie Tian, et al.
Published: (2020-10-01) -
In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology.
by: Suvas, S, et al.
Published: (2005) -
Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.
by: You, S, et al.
Published: (2005)