The molecular basis of Plasmodium falciparum merozoite invasion inhibition via anti-PfCyRPA antibodies

The molecular basis of Plasmodium falciparum merozoite invasion inhibition via anti-PfCyRPA antibodies

<p><em>Plasmodium falciparum</em>, the pathogen responsible for the deadliest form of malaria, continues to exact an immense human toll, disproportionality shouldered by countries in sub-Saharan Africa. Significant progress has been made this century in reducing global malaria mort...

Bibliográfalaš dieđut
Váldodahkki:	Ragotte, R
Eará dahkkit:	Draper, S
Materiálatiipa:	Oahppočájánas
Giella:	English
Almmustuhtton:	2020
Fáttát:	Immunology Biochemistry Monoclonal antibodies Malaria

Geahča maid

The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
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Almmustuhtton: (2023)

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Expanding the Malaria Antibody Toolkit: Development and Characterisation of Plasmodium falciparum RH5, CyRPA, and CSP Recombinant Human Monoclonal Antibodies
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Almmustuhtton: (2022-06-01)

Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
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Almmustuhtton: (2017-02-01)

The essential malaria protein PfCyRPA targets glycans to invade erythrocytes
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Leveraging Immunofocusing and Virus-like Particle Display to Enhance Antibody Responses to the Malaria Blood-Stage Invasion Complex Antigen PfCyRPA
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Almmustuhtton: (2024-07-01)

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Insights into the design of an improved PfRH5 malaria immunogen using vaccine-induced monoclonal antibodies
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Identification and characterisation of candidate monoclonal antibody Ebolavirus therapeutics
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Almmustuhtton: (2017-02-01)

Structural investigation of receptor engagement and monoclonal antibodies targeting Plasmodium vaccine antigens
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Almmustuhtton: (2023)

Characterization of antibody-antigen interactions using biolayer interferometry
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Almmustuhtton: (2021-12-01)

Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein
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Almmustuhtton: (2020-03-01)

Generation and characterisation of monoclonal antibodies specific to Plasmodium falciparum enolase
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Almmustuhtton: (2006-06-01)

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites.
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Almmustuhtton: (2008-07-01)

Identification of a Novel RAMA/RON3 Rhoptry Protein Complex in Plasmodium falciparum Merozoites
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Producción y caracterización de un anticuerpo monoclonal que reconoce el fragmento 28-30 kDa de la proteína MSP-1 de Plasmodium falciparum
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Plasmodium falciparum transmission based on merozoite surface protein 1 (msp1) and 2 (msp2) gene diversity and antibody responses in Ibadan, Nigeria
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Almmustuhtton: (2024-08-01)

Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains.
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Almmustuhtton: (2011-06-01)

Framework for Characterizing Longitudinal Antibody Response in Children After Plasmodium falciparum Infection
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A Molecular Analysis of Memory B Cell and Antibody Responses Against Plasmodium falciparum Merozoite Surface Protein 1 in Children and Adults From Uganda
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Characterization of a novel Plasmodium falciparum merozoite surface antigen and potential vaccine target
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Therapeutic monoclonal antibody for Sporotrichosis
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Standardization and validation of a cytometric bead assay to assess antibodies to multiple <it>Plasmodium falciparum</it> recombinant antigens
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Process development and preclinical evaluation of a major Plasmodium falciparum blood stage vaccine candidate, Cysteine-Rich Protective Antigen (CyRPA)
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