Enterovirus-like particles encapsidate RNA and exhibit decreased stability due to lack of maturation

To counteract hand, foot, and mouth disease-causing viruses such as enterovirus A71 and coxsackievirus A6, virus-like particles (VLPs) have emerged as a leading contender for the development of a multivalent vaccine. However, VLPs have shown rapid conversion from a highly immunogenic state to a less...

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Bibliographic Details
Main Authors: Kuijpers, L, Giannopoulou, E, Feng, Y, van den Braak, W, Freydoonian, A, Ramlal, R, Meiring, H, Solano, B, Roos, WH, Jakobi, AJ, van der Pol, LA, Dekker, NH
Format: Journal article
Language:English
Published: Public Library of Science 2025