An analysis of B cell selection mechanisms in germinal centers.
Affinity maturation of antibodies during immune responses is achieved by multiple rounds of somatic hypermutation and subsequent preferential selection of those B cells that express B cell receptors with improved binding characteristics for the antigen. The mechanism underlying B cell selection has...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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