RelB/p50 regulates CCL19 production, but fails to promote human DC maturation.
DC, when fully matured are the APC best able to activate naïve T cells. Recently, we demonstrated using adenoviruses overexpressing IkappaBalpha and proteosome inhibitors that NF-kappaB is involved in DC activation, but the role of the individual subunits is still not clear. We investigated the role...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2009
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