OTULIN deficiency causes auto-inflammatory syndrome
Ubiquitin chains assembled via the N-terminal methionine (Met1; or linear ubiquitin), conjugated by the linear ubiquitin chain assembly complex (LUBAC), participate in NF- dependent inflammatory signaling and immune responses. A recent report in Cell finds that OTULIN, a deubiquitinase that select...
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| Format: | Journal article |
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Nature Publishing Group
2016
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