Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner

Vδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species...

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Bibliographic Details
Main Authors:	Provine, NM, Amini, A, Garner, LC, FitzPatrick, MEB, Dold, C, Reyes, LS, Chinnakannan, S, Oguti, B, Raymond, M, Troise, F, Capone, S, Folgori, A, Barnes, E, Rollier, CS, Pollard, AJ, Klenerman, P
Format:	Journal article
Language:	English
Published:	Wiley 2022

Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner

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