Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner
Vδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
Wiley
2022
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| _version_ | 1826308210745671680 |
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| author | Provine, NM Amini, A Garner, LC FitzPatrick, MEB Dold, C Reyes, LS Chinnakannan, S Oguti, B Raymond, M Troise, F Capone, S Folgori, A Barnes, E Rollier, CS Pollard, AJ Klenerman, P |
| author_facet | Provine, NM Amini, A Garner, LC FitzPatrick, MEB Dold, C Reyes, LS Chinnakannan, S Oguti, B Raymond, M Troise, F Capone, S Folgori, A Barnes, E Rollier, CS Pollard, AJ Klenerman, P |
| author_sort | Provine, NM |
| collection | OXFORD |
| description | Vδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species C origin, including the ChAdOx1 vaccine platform. |
| first_indexed | 2024-03-07T07:16:06Z |
| format | Journal article |
| id | oxford-uuid:f4fe332c-d4ad-4bd1-b404-9da390118a84 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:16:06Z |
| publishDate | 2022 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:f4fe332c-d4ad-4bd1-b404-9da390118a842022-08-05T09:24:23ZAdenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent mannerJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f4fe332c-d4ad-4bd1-b404-9da390118a84EnglishSymplectic ElementsWiley2022Provine, NMAmini, AGarner, LCFitzPatrick, MEBDold, CReyes, LSChinnakannan, SOguti, BRaymond, MTroise, FCapone, SFolgori, ABarnes, ERollier, CSPollard, AJKlenerman, PVδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species C origin, including the ChAdOx1 vaccine platform. |
| spellingShingle | Provine, NM Amini, A Garner, LC FitzPatrick, MEB Dold, C Reyes, LS Chinnakannan, S Oguti, B Raymond, M Troise, F Capone, S Folgori, A Barnes, E Rollier, CS Pollard, AJ Klenerman, P Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title | Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title_full | Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title_fullStr | Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title_full_unstemmed | Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title_short | Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner |
| title_sort | adenovirus vectors activate vδ2 γδt cells in a type i interferon tnf and il 18 dependent manner |
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