Insights into L-type heteromeric amino acid transporters

Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.

ग्रंथसूची विवरण
मुख्य लेखक: Newstead, S
स्वरूप: Journal article
भाषा:English
प्रकाशित: Nature Research 2019
विवरण
सारांश:Two recent cryo-EM structures of the human L-type heteromeric amino acid transporter LAT1–CD98hc reveal surprising new insights into both amino acid transport in the human body and the roles of CD98hc as a cell-surface antigen and trafficking chaperone.