Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.

Membrane-type 1 matrix metalloproteinase (MT1-MMP/MMP-14) is an enzyme that promotes tumor cell invasion in tissues. Although the proteolytic activity of MT1-MMP is indispensable for invasion, it is also regulated by functions of the cytoplasmic tail. In this study we obtained a new human gene whose...

Full description

Bibliographic Details
Main Authors: Uekita, T, Gotoh, I, Kinoshita, T, Itoh, Y, Sato, H, Shiomi, T, Okada, Y, Seiki, M
Format: Journal article
Language:English
Published: 2004