Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children.
Haptoglobin (Hp) scavenges free hemoglobin following malaria-induced hemolysis. Few studies have investigated the relationship between the common Hp variants and the risk of severe malaria, and their results are inconclusive. We conducted a case-control study of 996 children with severe Plasmodium f...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society of Hematology
2014
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