Epistasis between the haptoglobin common variant and α+thalassemia influences risk of severe malaria in Kenyan children.

Haptoglobin (Hp) scavenges free hemoglobin following malaria-induced hemolysis. Few studies have investigated the relationship between the common Hp variants and the risk of severe malaria, and their results are inconclusive. We conducted a case-control study of 996 children with severe Plasmodium f...

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Bibliographic Details
Main Authors: Atkinson, S, Uyoga, S, Nyatichi, E, Macharia, A, Nyutu, G, Ndila, C, Kwiatkowski, D, Rockett, K, Williams, T
Format: Journal article
Language:English
Published: American Society of Hematology 2014