Overcoming monocarboxylate transporter 8 (MCT8)-deficiency to promote human oligodendrocyte differentiation and myelination

Cell membrane thyroid hormone (TH) transport can be facilitated by the monocarboxylate transporter 8 (MCT8), encoded by the solute carrier family 16 member 2 (SLC16A2) gene. Human mutations of the gene, SLC16A2, result in the X-linked-inherited psychomotor retardation and hypomyelination disorder, A...

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Bibliographic Details
Main Authors: Lee, JY, Kim, MJ, Deliyanti, D, Azari, MF, Rossello, F, Costin, A, Ramm, G, Stanley, EG, Elefanty, AG, Wilkinson-Berka, JL, Petratos, S
Format: Journal article
Language:English
Published: Elsevier 2017