Germline HNPCC gene variants have little influence on the risk for sporadic colorectal cancer.

Hereditary non-polyposis colorectal cancer (HNPCC) is a syndrome of inherited bowel and other cancers that has been said to account for up to 15% of all colorectal carcinomas (CRCs). HNPCC can now be diagnosed at the molecular level by detecting germline mutations in genes involved in mismatch repai...

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Bibliografski detalji
Glavni autori: Tomlinson, I, Beck, N, Homfray, T, Harocopos, C, Bodmer, W
Format: Journal article
Jezik:English
Izdano: 1997