Cellular and molecular pharmacology of the lipid-sensitive channel TMEM16A/Anoctamin1
TMEM16A Ca2+-activated Cl- channels (CaCC) control vital functions including arterial smooth muscle tone and blood flow. The TMEM16A has a pore with regions surrounding plasmalemmal lipids, an arrangement where lipids can directly influence the ion permeation and gating of the channel. Here, it is h...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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