Factor inhibiting HIF can catalyse two asparaginyl-hydroxylations in VNVN motifs of ankyrin fold proteins
The aspariginyl-hydroxylase human Factor Inhibiting HIF (FIH) is an important regulator of the transcriptional activity of hypoxia inducible factor (HIF). FIH also catalyses the hydroxylation of asparaginyl and other residues in ankyrin repeat domain (ARD) containing proteins, including apoptosis st...
Hoofdauteurs: | Leissing, TM, Hardy, AP, Chan, H, Wang, Y, Tumber, A, Chowdhury, R, Fang, P, Coleman, ML, Cockman, ME, Kramer, HB, Berridge, G, Fischer, R, Kessler, B, Ratcliffe, PJ, Lu, X, Schofield, CJ |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Elsevier
2022
|
Gelijkaardige items
-
FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
door: Cockman, M, et al.
Gepubliceerd in: (2009) -
Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.
door: Coleman, M, et al.
Gepubliceerd in: (2007) -
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
door: Cockman, M, et al.
Gepubliceerd in: (2006) -
Biochemical and structural insights into FIH-catalysed hydroxylation of transient receptor potential ankyrin repeat domains
door: Saward, B, et al.
Gepubliceerd in: (2022) -
Asparaginyl beta-hydroxylation of proteins containing ankyrin repeat domains influences their stability and function.
door: Hardy, A, et al.
Gepubliceerd in: (2009)