Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether‐lumefantrine for uncomplicated malaria

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether‐lumefantrine for uncomplicated malaria

Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs. This population pharmacokinetic (PK)‐pharmacodynamic study included 131 SAM and 266 non‐SAM children administered...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Chotsiri, P, Denoeud-Ndam, L, Baudin, E, Guindo, O, Diawara, H, Attaher, O, Smit, M, Guerin, PJ, Doumbo, OK, Wiesner, L, Barnes, KI, Hoglund, RM, Dicko, A, Etard, J-F, Tarning, J
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: American Society for Clinical Pharmacology and Therapeutics 2019

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