Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether‐lumefantrine for uncomplicated malaria
Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub‐Saharan African children and may affect the pharmacology of antimalarial drugs. This population pharmacokinetic (PK)‐pharmacodynamic study included 131 SAM and 266 non‐SAM children administered...
Главные авторы: | Chotsiri, P, Denoeud-Ndam, L, Baudin, E, Guindo, O, Diawara, H, Attaher, O, Smit, M, Guerin, PJ, Doumbo, OK, Wiesner, L, Barnes, KI, Hoglund, RM, Dicko, A, Etard, J-F, Tarning, J |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
American Society for Clinical Pharmacology and Therapeutics
2019
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