Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Hypoxia-inducible factor (HIF) mediates a large number of transcriptional responses to hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. The HIF DNA binding complex consists of 2 basic-helix-loop-helix PAS proteins designated alpha and beta subunits. Regula...

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Hlavní autoři: Vaux, E, Metzen, E, Yeates, K, Ratcliffe, P
Médium: Journal article
Jazyk:English
Vydáno: 2001

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