Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Hypoxia-inducible factor (HIF) mediates a large number of transcriptional responses to hypoxia and has an important role in processes that include angiogenesis and erythropoiesis. The HIF DNA binding complex consists of 2 basic-helix-loop-helix PAS proteins designated alpha and beta subunits. Regula...

Полное описание

Библиографические подробности
Главные авторы:	Vaux, E, Metzen, E, Yeates, K, Ratcliffe, P
Формат:	Journal article
Язык:	English
Опубликовано:	2001

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