Epistasis in sporadic Alzheimer's disease.

The traditional approach in case-control association studies, to evaluate candidate genes individually, either single markers or haplotypes, has had limited success. The multifactorial nature of complex diseases suggests the alternative of examining gene-gene interactions (epistasis) within biologic...

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Bibliographic Details
Main Authors: Combarros, O, Cortina-Borja, M, Smith, A, Lehmann, D
Format: Journal article
Language:English
Published: 2009