Epistasis in sporadic Alzheimer's disease.
The traditional approach in case-control association studies, to evaluate candidate genes individually, either single markers or haplotypes, has had limited success. The multifactorial nature of complex diseases suggests the alternative of examining gene-gene interactions (epistasis) within biologic...
Main Authors: | Combarros, O, Cortina-Borja, M, Smith, A, Lehmann, D |
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格式: | Journal article |
语言: | English |
出版: |
2009
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