Contact between good friends: what limiting dilution analysis taught us.
The demonstration in the 1960s that T cells collaborated with B cells in enabling antibody responses to simple protein antigens opened up the challenge of how to investigate the interactions of two rare antigen-specific lymphocytes within a vast population. One idea was that T cells made soluble fac...
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Format: | Journal article |
Language: | English |
Published: |
2005
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