The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis

As a first host barrier, the skin is constantly exposed to environmental insults that perturb its integrity. Tight regulation of skin homeostasis is largely controlled by the aryl hydrocarbon receptor (AhR). Here, we demonstrate that Henna and its major pigment, the naphthoquinone Lawsone activate A...

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Bibliographic Details
Main Authors: Lozza, L, Moura Alves, P, Domaszewska, T, Lage Crespo, C, Streata, I, Kreuchwig, A, Puyskens, A, Bechtle, M, Klemm, M, Zedler, U, Ungureanu Bogdan, S, Guhlich-Bornhof, U, Koehler, A, Staeber, M, Mollenkopf, H, Hurwitz, R, Furkert, J, Krause, G, Weiner 3Rd, J, Mihai, I, Jacinto, A, Leite-De-Moraes, M, Siebenhaar, F, Maurer, M, H.E.Kaufmann, S
Format: Journal article
Language:English
Published: Nature 2019