The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats

On the basis of tissue-specific enzyme activity and inhibition by catalytic products, Hans Krebs first demonstrated the existence of multiple glutaminases in mammals. Currently, two human genes are known to encode at least four glutaminase isoforms. However, the phylogeny of these medically relevant...

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Bibliographic Details
Main Authors: Pascoal, C, Islam, Z, Adamoski, D, Ferreira, I, Righetto, R, Bettini, J, Portugal, R, Yue, W, Gonzalez, A, Dias, S, Ambrosio, A
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2017