Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction

A single HIV-1 variant establishes infection of the host after sexual contact. Identifying the phenotypic characteristics of these Transmitted Founder (T/F) viruses is important to understand the restriction mechanisms during transmission. Langerhans cells (LCs) are the mucosal dendritic cell subset...

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Bibliographic Details
Main Authors: Borrow, P, Fenton-May, A
Format: Journal article
Published: Public Library of Science 2019