The cohesin ring concatenates sister DNA molecules.

Sister chromatid cohesion, which is essential for mitosis, is mediated by a multi-subunit protein complex called cohesin. Cohesin's Scc1, Smc1 and Smc3 subunits form a tripartite ring structure, and it has been proposed that cohesin holds sister DNA molecules together by trapping them inside it...

Full description

Bibliographic Details
Main Authors: Haering, C, Farcas, A, Arumugam, P, Metson, J, Nasmyth, K
Format: Journal article
Language:English
Published: 2008