The importance of clinical importance when determining the target difference in sample size calculations
Recently, it was argued that clinically important differences should play no role in sample size calculations. Instead, it was proposed that sample size calculations should focus on setting realistic estimates of treatment benefit. We disagree, and argue in this article that considering the importan...
Egile Nagusiak: | Parker, RA, Cook, JA |
---|---|
Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
BioMed Central
2023
|
Antzeko izenburuak
-
Response to Letter from Wong on determining the target difference in sample size calculations for randomised controlled trials
nork: Cook, JA, et al.
Argitaratua: (2024) -
Guidance on minimally important clinical difference and trial size is needed.
nork: Cook, J, et al.
Argitaratua: (2011) -
Sample size calculations in clinical research /
nork: Chow, Shein-Chung, 1955-, et al.
Argitaratua: (2008) -
Determining the minimum clinically important differences for outcomes in the DOMINO trial.
nork: Howard, R, et al.
Argitaratua: (2011) -
Developing clinical prediction models when adhering to minimum sample size recommendations: the importance of quantifying bootstrap variability in tuning parameters and predictive performance
nork: Martin, GP, et al.
Argitaratua: (2021)