Determination of the structure of a decay accelerating factor-binding clinical isolate of echovirus 11 allows mapping of mutants with altered receptor requirements for infection.

We have used X-ray crystallography to determine the structure of a decay accelerating factor (DAF)-binding, clinic-derived isolate of echovirus 11 (EV11-207). The structures of the capsid proteins closely resemble those of capsid proteins of other picornaviruses. The structure allows us to interpret...

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Hlavní autoři: Stuart, A, McKee, T, Williams, P, Harley, C, Shen, S, Stuart, D, Brown, T, Lea, S
Médium: Journal article
Jazyk:English
Vydáno: 2002