Phenotypic models of T cell activation

T cell activation is a crucial checkpoint in adaptive immunity, and this activation depends on the binding parameters between the T cell receptor (TCR) and peptide-MHC (pMHC) complexes as well as the dose at which the pMHC is presented. Despite extensive experimental studies, it still remains contro...

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Bibliographic Details
Main Authors: Lever, M, Maini, P, Van Der Merwe, P, Dushek, O
Format: Conference item
Published: American Association of Immunologists 2015