Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses

Defending against future pandemics requires vaccine platforms that protect across a range of related pathogens. Nanoscale patterning can be used to address this issue. Here, we produce quartets of linked receptor-binding domains (RBDs) from a panel of SARS-like betacoronaviruses, coupled to a comput...

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Bibliographic Details
Main Authors: Hills, RA, Tan, TK, Cohen, AA, Keeffe, JR, Keeble, AH, Gnanapragasam, PNP, Storm, KN, Rorick, AV, West, AP, Hill, ML, Liu, S, Gilbert-Jaramillo, J, Afzal, M, Napier, A, Admans, G, James, WS, Bjorkman, PJ, Townsend, AR, Howarth, MR
Format: Journal article
Language:English
Published: Nature Research 2024